Junyan Ma
ORCID: 0000-0003-1162-1227
· 40 papers in corpus
lab-animal
2025
Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and regulator of disease progres…
other
2023
Increasing evidences showed that ovulatory dysfunction, possibly caused by luteinized unruptured follicular follicle syndrome (LUFS), is one of the reasons for endometriosis-related infertility. The present study was conducted to explore th…
observational
2022
Female fertility declines with age, and this natural variation culminates in reproductive senescence. Human follicular fluids are rich in low-molecular weight metabolites which are responsible for the maturation of oocytes. The metabolomic …
2021
Additional file 10. Differentially expressed genes of all M cells subclusters.
lab-animal
2021
Additional file 11. Differentially expressed genes of FB clusters among endometriosis lesions, eutopic endometrium, and normal endometrium.
2021
Additional file 12. Differentially expressed genes of CD4+ T cells along the pseudotime trajectory.
2021
Additional file 1: Figure S1. Study flow chart. Single-cell RNA-sequencing. Figure S2 a-g. Enriched functions of FBs, Eps, ECs, T cells, NK cells, M cells, ast cells and neutrophils by GO and KEGG analyses. Figure S3. Single-cell RNA-seq an…
2021
Additional file 3. Differentially expressed genes of FBs, M cells, NK cells, T cells, ECs, Eps, mast cells, and neutrophils.
2021
Additional file 4. Differentially expressed genes of all FBs subclusters.
2021
Additional file 5. Differentially expressed genes of FBs along the pseudotime trajectory.
2021
Additional file 6. The relative ratio of immune cells in endometriosis lesions, eutopic endometrium, and normal endometrium.
2021
Additional file 7. Differentially expressed genes of all T cells subclusters.
2021
Additional file 8. The relative ratio of T cells subclusters in endometriosis lesions, eutopic endometrium, and normal endometrium.
2021
Additional file 9. Differentially expressed genes of all NK cells subclusters.
2021
Abstract Background: Luteinized unruptured follicular follicle syndrome (LUFS) is a special type of ovulatory dysfunction and a common cause of infertility. It is estimated that its prevalence is 13% ~ 73% in endometriosis patients. Increa…
other
2021
BACKGROUND: Endometriosis is a benign gynecological disease that shares some characteristics with malignant tumors and affects approximately 10% of women of reproductive age. Endometrioma refers to endometriosis that appears in the ovary. M…
other
2021
BACKGROUND: Endometriosis is an oestrogen-dependent disease with an unclear aetiology and pathogenesis affecting 6-10% of the global female population, predominantly those of reproductive age. Herein, we profile the transcriptomes of approx…
2021
lab-animal
2020
OBJECTIVE: To investigate the role(s) of hyaluronan synthase 2 (HAS2) and hyaluronan in disease progression of endometriosis and epidermal growth factor (EGF)-induced motility changes of endometriotic cells. DESIGN: A case-control experime…
other
2020
Identification of key genes and pathways in endometriosis by integrated expression profiles analysis
The purpose of this study was to integrate the existing expression profile data on endometriosis (EM)-related tissues in order to identify the differentially expressed genes. In this study, three series of raw expression data were downloade…
lab-animal
2020
BACKGROUND: Endometriosis is a benign gynaecological disease with malignant characteristics that severely affects women's quality of life. Long noncoding RNA maternally expressed gene 3 (LncRNA MEG3) is a tumour suppressor that is downregul…
lab-animal
2019
Interleukin (IL)-34 plays a critical role in cell proliferation, differentiation, apoptosis, angiogenesis, inflammation and immunoregulation. Numerous diseases can be attributed to the dysregulation of IL-34 signaling. This study was perfor…
lab-animal
2019
RESEARCH QUESTION: Endometriosis is characterized by the occurrence of endometrial-like tissue outside the uterus. Collagen triple helix repeat containing-1 (CTHRC1) is known as a tumour-promoting factor in several neoplasms. This study aim…
other
2019
The purpose of this study was to investigate the difference of Twist gene promoter methylation among ovarian ectopic endometrium, eutopic endometrium and non-endometriosis (EMs) endometrium . 15 patients with reproductive age hospitalized a…
lab-animal
2019
AIM: To investigate the roles of cell migration and invasion mediated by Twist in endometriosis. METHODS: The protein levels and locations of Twist, N-cadherin and E-cadherin were measured by Western blot and immunohistochemistry in ectopi…