Tomoko Akahane

No ORCID on file · 4 papers in corpus · active 2004-2010

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 4
  • mesh:D004715 3
article 2010
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese
Nature genetics ·doi:10.1038/ng.612
article 2007
The Role of p53 Mutation in the Carcinomas Arising from Endometriosis
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e31802b41a8

To probe the mechanism of the development of ovarian cancer from endometriosis, which is a multistep process that involves the activation of oncogenes and inactivation of tumor suppressor genes, we evaluated p53 mutations in solitary endome…

other 2005
Disappearance of steroid hormone dependency during malignant transformation of ovarian clear cell cancer
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/01.pgp.0000165173.90339.a2

Ovarian clear-cell carcinoma (OCCA) and ovarian endometrioid carcinoma (OEMC) are often associated with endometriosis. This study determined the immunohistochemical expression of steroid hormone receptors and cancer-related genes in OCCA an…

article 2004
Relationship between Malignant Transformation of Endometriosis and Genetic Alterations of K-ras and Microsatellite Instability
·doi:10.15369/sujms1989.16.47

Several genetic alterations have been associated with the malignant transformation from endometriosis to ovarian cancer. However, the role of each genetic alteration in this multi-step process of tumorigenesis has not been clarified. Region…