Anna Starzinski‐Powitz

ORCID: 0000-0003-4552-4193 · 59 papers in corpus
2020
Faculty Opinions recommendation of Biological characteristics of endometriotic mesenchymal stem cells isolated from ectopic lesions of patients with endometriosis.
·doi:10.3410/f.738472211.793581420
2019
Faculty Opinions recommendation of Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis.
·doi:10.3410/f.734525924.793563223
2019
Faculty Opinions recommendation of Extracellular vesicles from endometriosis patients are characterized by a unique miRNA-lncRNA signature.
·doi:10.3410/f.736652736.793567504
2018
Faculty Opinions recommendation of CD147 Induces Epithelial-to-Mesenchymal Transition by Disassembling Cellular Apoptosis Susceptibility Protein/E-Cadherin/β-Catenin Complex in Human Endometriosis.
·doi:10.3410/f.733018328.793554373
lab-animal 2018
Lysophosphatidic acid triggers cathepsin B-mediated invasiveness of human endometriotic cells
Biochimica et biophysica acta. Molecular and cell biology of lipids ·doi:10.1016/j.bbalip.2018.08.013

Extracellular lysophosphatidic acid (LPA) and the G-protein-coupled LPA receptors (LPAR) are involved in cell migration and invasion and found in the human endometrium. However, underlying mechanisms resulting in cellular invasion have been…

2017
Faculty Opinions recommendation of The gut microbiota: a puppet master in the pathogenesis of endometriosis?
·doi:10.3410/f.726166146.793529358
review 2017
Molecular and Cellular Pathogenesis of Endometriosis
Current women's health reviews ·doi:10.2174/1573404813666170306163448

BACKGROUND: A substantial body of studies supports the view that molecular and cellular features of endometriotic lesions differ from those of eutopic endometrium. Apart from that, evidence exists that the eutopic endometrium from pa-tients…

2016
Faculty Opinions recommendation of 17 β-Estradiol promotes vascular endothelial growth factor expression via the Wnt/β-catenin pathway during the pathogenesis of endometriosis.
·doi:10.3410/f.726232653.793516381
2016
Faculty Opinions recommendation of Estrogen receptor β modulates apoptosis complexes and the inflammasome to drive the pathogenesis of endometriosis.
·doi:10.3410/f.725917202.793519047
2016
Faculty Opinions recommendation of Impaired development of early endometriotic lesions in CD44 knockout mice.
·doi:10.3410/f.725641013.793526676
lab-animal 2016
microRNA miR-200b affects proliferation, invasiveness and stemness of endometriotic cells by targeting ZEB1, ZEB2 and KLF4
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2015.12.013

Endometriosis is characterized by growth of endometrial tissue at ectopic locations. Down-regulation of microRNA miR-200b is observed in endometriosis and malignant disease, driving tumour cells towards an invasive state by enhancing epithe…

lab-animal 2016
PAI-1 secretion of endometrial and endometriotic cells is Smad2/3- and ERK1/2-dependent and influences cell adhesion
American journal of translational research ·doi:10.22029/jlupub-8634

In the endometrium transforming growth factor-betas (TGF-βs) are involved mainly in menstruation and endometriosis. After binding of the ligands to the high-affinity receptors, TGF-β receptors (TBR1 and TBR2), TGF-βs activate Smad signaling…

other 2016
Syndecan-4 expression is upregulated in endometriosis and contributes to an invasive phenotype
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.03.032

OBJECTIVE: To study the expression and function of syndecan-4 in endometriosis. DESIGN: Histopathological investigation of eutopic endometrium and experimental laboratory study on a cell line derived from epithelial endometriotic cells (12…

2015
Faculty Opinions recommendation of Estradiol promotes cells invasion by activating β-catenin signaling pathway in endometriosis.
·doi:10.3410/f.725835847.793512577
2015
Faculty Opinions recommendation of The WNT/β-catenin signaling pathway and expression of survival promoting genes in luteinized granulosa cells: endometriosis as a paradigm for a dysregulated apoptosis pathway.
·doi:10.3410/f.718323496.793506872
lab-animal 2015
Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1507931112

Endometriosis is a debilitating, estrogen-dependent, progesterone-resistant, inflammatory gynecological disease of reproductive age women. Two major clinical symptoms of endometriosis are chronic intolerable pelvic pain and subfertility or …

lab-animal 2015
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 modulates DNA methylation and histone modification machinery proteins in human endometriotic cells
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2015.03.023

Endometriosis is an inflammatory gynecological disease of reproductive-age women. The prevalence of endometriosis is 5-10% in reproductive-age women. Modern medical treatments are directed to inhibit the action of estrogen in endometriotic …

2014
Faculty Opinions recommendation of Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation.
·doi:10.3410/f.718266830.793491980
2013
Faculty Opinions recommendation of ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling.
·doi:10.3410/f.718021238.793478998
2013
Faculty Opinions recommendation of HDAC1 and HDAC2 are differentially expressed in endometriosis.
·doi:10.3410/f.717988609.793472691
2013
Faculty Opinions recommendation of In vitro effects of a small-molecule antagonist of the Tcf/ß-catenin complex on endometrial and endometriotic cells of patients with endometriosis.
·doi:10.3410/f.718003734.793486663
2013
Faculty Opinions recommendation of SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis.
·doi:10.3410/f.718029869.793481313
2012
Faculty Opinions recommendation of Paired-box gene 2 is down-regulated in endometriosis and correlates with low epidermal growth factor receptor expression.
·doi:10.3410/f.716748313.792103367
2012
Faculty Opinions recommendation of Sorafenib inhibits growth, migration, and angiogenic potential of ectopic endometrial mesenchymal stem cells derived from patients with endometriosis.
·doi:10.3410/f.717956449.793466961
lab-animal 2012
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion of human endometriotic epithelial and stromal cells through suppression of integrin-mediated mechanisms
Biology of reproduction ·doi:10.1095/biolreprod.112.100883

Endometriosis is a chronic gynecological disease of reproductive age women characterized by the presence of functional endometrial tissues outside the uterine cavity. Interactions between the endometriotic cells and the peritoneal extracell…