Takuya Sugahara

No ORCID on file · 4 papers in corpus · active 2019-2023

Study types

  • article 4

Condition tags

  • endometriosis 4
  • mesh:D004715 3
  • endometrioma 2
article 2023
Hepcidin as a key regulator of iron homeostasis triggers inflammatory features in the normal endometrium
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2023.10.402

Menstrual blood, containing high iron levels, can undergo retrograde transport into the abdominal cavity. Excess iron causes oxidative stress and inflammation. Iron metabolism is regulated by hepcidin, and serum hepcidin levels are increase…

article 2021
Reduced innate lymphoid cells in the endometrium of women with endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13502

PROBLEM: Innate lymphoid cells (ILCs), a recently discovered family of innate immune cells, are responsible for the early immune response, and control both innate and adapted immune system via cytokine secretion. The role of ILCs in endomet…

article 2020
Atherosclerosis-related biomarkers in women with endometriosis: The effects of dienogest and oral contraceptive therapy
European journal of obstetrics & gynecology and reproductive biology: X ·doi:10.1016/j.eurox.2020.100108

Chronic inflammation in endometriosis is associated with increased risk of future cardiovascular disease; however, no studies have investigated the cardiovascular risk of women who have undergone hormonal therapy for endometriosis. We inves…

article 2019
Peroxisome proliferator-activated receptor-γ coactivator 1α-mediated pathway as a possible therapeutic target in endometriosis
Human Reproduction ·doi:10.1093/humrep/dez067

STUDY QUESTION: Is a peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α)-mediated pathway involved in the development of endometriosis? SUMMARY ANSWER: PGC-1α plays critical roles in inflammation and cell proliferation of e…