Fernando O. Martínez

ORCID: 0000-0003-0908-9366 · 5 papers in corpus
other 2021
Science translational medicine ·doi:10.1126/scitranslmed.abd6469

Endometriosis is a common chronic inflammatory condition causing pelvic pain and infertility in women, with limited treatment options and 50% heritability. We leveraged genetic analyses in two species with spontaneous endometriosis, humans …

observational 2020
BMC medicine ·doi:10.1186/s12916-019-1470-y

BACKGROUND: Endometriosis is a gynaecological condition characterised by immune cell infiltration and distinct inflammatory signatures found in the peritoneal cavity. In this study, we aim to characterise the immune microenvironment in samp…

2018

The G-protein coupled receptor GPR84 binds and becomes activated by saturated medium-chain free fatty acids, is expressed on pro-inflammatory macrophages and pharmacological inhibition leads to reduction of inflammatory markers.

2016
review 2014
Immunological reviews ·doi:10.1111/imr.12223

During development and throughout adult life, macrophages derived from hematopoietic progenitors are seeded throughout the body, initially in the absence of inflammatory and infectious stimuli as tissue-resident cells, with enhanced recruit…