Osamu Tanizawa

No ORCID on file · 7 papers in corpus
lab-animal 1993
In vivo (Athens, Greece)

The effects of danazol on estrogen production by rat ovaries were investigated. Hypophysectomized immature female rats were injected daily with 2.5 or 5 IU of pregnant mare serum gonadotropin (PMS) and simultaneously daily given vehicle onl…

other 1991
European Journal of Obstetrics & Gynecology and Reproductive Biology ·doi:10.1016/0028-2243(91)90056-q

To determine the effects of nocturnal hyperprolactinemia on luteal function and galactorrhea we studied six diurnal normoprolactinemic women with regular menstrual cycles. The diurnal serum levels of prolactin (PRL), luteinizing hormone (LH…

lab-animal 1990
American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(90)90650-v

Effects of danazol, gonadotropin-releasing hormone agonist (leuprolide), and danazol-leuprolide combination on experimental endometriosis were evaluated in female rats. A complete resorption of the fluid and a marked decrease in the volume …

nonrandomized-trial 1989
Endocrinologia japonica ·doi:10.1507/endocrj1954.36.611

The chronic administration of GnRH agonists to women results in the reversible suppression of estrogen production by the ovary. In the present study, the mechanism of the GnRH agonist suppression of estrogen production was investigated in p…

other 1988
Cancer ·doi:10.1002/1097-0142(19881215)62:12<2618::aid-cncr2820621228>3.0.co;2-i

Since the authors recently reported that danazol inhibits the growth of human endometrial cancer cells in vitro, a clinical trial was initiated to examine whether danazol can regress adenomatous hyperplasia, a precursor of endometrial adeno…

lab-animal 1987
Journal of steroid biochemistry ·doi:10.1016/0022-4731(87)90517-6

Since we recently found that danazol, an isoxazol derivative of ethinyltestosterone, has a growth-inhibitory effect on human endometrial cancer cells in primary culture, the effects of danazol on a human endometrial cancer cell line (IK-90 …

lab-animal 1986
American journal of obstetrics and gynecology ·doi:10.1016/s0002-9378(86)80039-4

Based on our recent findings that danazol, an isoxazol derivative of ethinyltestosterone, has a profound growth-inhibitory effect on an established human endometrial adenocarcinoma cell line, the effects of danazol on cancer cells from huma…