Aim Angiogenesis plays an important role in the pathogenesis of endometriosis. Thus, the inhibition of angiogenesis may prevent endometriosis. Bevacizumab is a recombinant humanized monoclonal antibody against VEGF. The aim of this study is…
OBJECTIVE: To determine the efficacy of anti-tumor necrosis factor therapy (etanercept) for treating endometriosis in the rat endometriosis model. STUDY DESIGN: A randomized, placebo-controlled, blinded study using rat endometriosis model.…
OBJECTIVE: To evaluate the effect of two different laparoscopic methods on ovarian reserve as determined by antral follicle count (AFC) and ovarian volume in patients with bilateral endometriomas. DESIGN: Randomized prospective study. SET…
AbstractEndometriosis is often associated with female infertility and exhibits a massive impairment in the physiology of uterine contractility that interferes with sperm and/or embryo movements. We present an unusual case of bilateral tubal…
OBJECTIVE: To show the efficacy of anti-tumor necrosis factor therapy (etanercept) for treating endometriosis in an experimental model. DESIGN: A randomized, placebo-controlled, blinded study using rat endometriosis model. SETTING: Experi…
The effect of immunomodulator leflunomide on the development of an experimental endometriosis model was assessed by surgically transplanting autologous fragments of endometrial tissue onto the inner surface of the abdominal wall and arteria…
OBJECTIVE: To test if leflunomide, an immunomodulator, could impede the growth of an ectopic uterine tissue. METHODS: Endometriosis was surgically induced in 26 rats by transplanting an autologous fragment of endometrial tissue onto the in…
STUDY OBJECTIVE: To describe a technique of uterine suspension using round ligaments to relieve pain in selected patients with various degrees of uterine retroversion. DESIGN: Prospective clinical study (Canadian Task Force classification …
Our purpose was to assess the most proper time for initiation of gonadotropin-releasing hormone agonist (GnRH-a) therapy combined with laparoscopic drainage. The first group included 13 women with 18 endometriomas (5 bilaterally) in whom dr…
To assess the efficacy of GnRH-agonist therapy in the treatment of endometriomas with or without surgical intervention, 26 women with laparoscopically proven endometriomas larger than 3 cm were recruited to the study. Fourteen women with 19…
OBJECTIVE: To evaluate the correlation of preoperative pelvic examination and ultrasonography with the laparoscopic findings in 45 adolescent women with chronic pelvic pain. STUDY DESIGN: Between January 1, 1989, and December 31, 1992, 45 …
The levels of CA 125 in the serum was evaluated in 66 patients with endometriosis diagnosed and staged according to the revised American Fertility Society (AFS) classification via laparoscopy. The patients received a 6 month course of gonad…
OBJECTIVES: The aim of this study was to assess the treatment of endometriosis with a gonadotropin-releasing hormone (GnRH) agonist in terms of changes to the extent of disease and to CA 125 levels as well as to recurrence during follow-up.…
In order to assess the effectiveness of GnRH-agonist (GnRH-a) therapy in the treatment of endometriomas, with or without surgical intervention, 26 women with laparoscopically proven endometriomas, greater than 3 cm diameter were recruited t…