Imaging of Endometriosis With Total-body PET-CT (PET-Endo)

NCT07523997 · ctgov recruiting

Enrollment: 30
Start: 2026-04-08
Completion: 2027-12-31
Last updated: 2026-05-27
Has results: False
Countries: United Kingdom

Conditions

Endometriosis

Tagged with

endometriosis

Interventions

PET/CT DIAGNOSTIC_TEST
Hybrid positron emission tomography and computed tomography will be performed after intravenous administration of the 68Ga-FAPI or the 18F-GP1 radiotracer and images centred on the pelvis. Attenuation-correction CT will be performed before acquisition of PET data
PET/MRI DIAGNOSTIC_TEST
Hybrid PET/MRI will be performed on a 3T scanner with T1 mapping immediately after the PET/CT with images acquired centred on the pelvis after injection of buscopan
Buscopan 20 MG/ML Injectable Solution DRUG
IV injection prior to PET/MRI

Eligibility criteria

Inclusion Criteria: * Chronic pelvic pain * Clinical/radiological diagnosis of likely endometriosis and due to undergo confirmatory laparoscopy in the subsequent four months Exclusion Criteria: * Inability or unwilling to give informed consent * Actively trying to conceive, pregnant or breastfeeding * Post menopausal (no periods for \>12 months and not taking hormonal treatments to prevent periods or bilateral oophorectomy performed) * Previous hysterectomy * Confirmed or suspected pelvic malignancy * Contraindication to MRI (ferromagnetic material in the body, metallic device implantation or claustrophobia) * Contraindication to buscopan (e.g. glaucoma, unstable cardiac disease, arrythmias, myasthenia, previous hypersensitivity to buscopan) * Taking part in a CTIMP or interventional non-CTIMP study * Previous severe pelvic inflammatory disease * Previous peritonitis

License: public-domain-us · commercial use OK · attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine