Ultrastructural changes in endometriotic implants during the menstrual cycle.

In: Obstetrics and gynecology · 1981 · vol. 58(4) , pp. 465–73 · PMID:7197010 · W2416755962
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This ultrastructural study found that while ectopic endometrial glands largely resemble their uterine counterparts, specific ovulation-associated features like giant mitochondria were absent in endometriotic implants.

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Abstract

This report, the first ultrastructural study of endometriotic implants, compares the ectopic endometrium in 14 patients with that found in the uterus. The ultrastructural features of most of the glands of the ectopic endometrium resemble those of the corresponding glands lining the uterus. Specific ultrastructural characteristics associated with ovulation, such as giant mitochondria and nuclear channel systems, however, could not be detected in ectopic tissue. Although no pathognomonic electron microscopic characteristics were found in the ectopic endometrium, it was generally possible to assign each sample to a particular phase of the menstrual cycle.

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