The role of prostaglandins in the spontaneous motility of the fallopian tube

M G Elder, Murdoch G. Elder, Leslie Myatt, L Myatt, Gautam Chaudhuri, G Chaudhuri
Fertility and sterility · 1977 · vol. 28(1) , pp. 86–90 · doi:10.1016/s0015-0282(16)42322-8 · PMID:832721 · W2415468132
Other OA: closed CC0 ⤵ 3 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-10 ⓘ

This study investigated the function of prostaglandins in the spontaneous movement of the fallopian tube.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Spontaneous isometric contractions of the human fallopian tube were measured in vitro. The tubes were obtained during the follicular phase of the menstrual cycle in 16 experiments and during the luteal phase in 23 experiments. The area under the curve and the frequency of spontaneous isometric contractions, together with the amount of prostaglandins E and F produced by the tube, were measured. Using each tissue as its own control, the effects of adding indomethacin or papeverine to the tissue both were assessed. Indomethacin, a prostaglandin synthetase inhibitor, significantly reduced the prostaglandin output without affecting the tubal motility. By contrast, papaverine, which is a smooth muscle relaxant but not an inhibitor of prostaglandin synthesis, significantly reduced both motility and prostaglandin output. It is concluded that prostaglandins do not have a direct role in the regulation of the spontaneous motility of the human fallopian tube.

My notes (saved in your browser only)

MeSH descriptors

Fallopian Tubes Muscle Contraction Muscle Contraction Prostaglandins E Prostaglandins F Fallopian Tubes Fallopian Tubes Female Humans Indomethacin Indomethacin In Vitro Techniques Menstruation Papaverine Papaverine Prostaglandins E Prostaglandins F

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (2)

Cited by (3)

References (15)

Cited by (3)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:59:31.578486+00:00
License: CC0 · commercial use OK