Malignant neoplasms arising in endometriosis: clinicopathological study of 14 cases.

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AI-generated summary by claude@2026-06, 2026-06-08

This clinicopathological study reviewed 14 cases of malignant endometriosis diagnosed in women aged 37-70, detailing tumor types, locations, and immunohistochemical findings.

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Abstract

During the last 15-year period in our laboratory, 14 cases of malignant change of endometriosis were diagnosed in women 37-70 years of age. Seven cases were adenocarcinomas, one case was an adenosarcoma and six cases presented the morphology of endometrial stromal sarcoma. Eleven cases developed in various sites of the genital system (5/11 in the ovaries, 3/11 in the uterus 2/11 in the vagina, 1/11 in the tubal wall) and three cases in extragenital sites (1/3 in the omentum, 1/3 in the pelvis, 1/3 in the colon). Immunohistochemical investigation for the expression of cytokeratines, vimentin, hormonal receptors, E-cadherin, desmine and smooth muscle actin was performed by a streptavidin-biotin method. The immunopathology profile and follow-up results after therapy are presented.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometrial Neoplasms Endometriosis Adenocarcinoma Adenocarcinoma Adenosarcoma Adenosarcoma Adult Aged Endometrial Neoplasms Endometriosis Female Humans Middle Aged Ovarian Neoplasms Ovarian Neoplasms Sarcoma, Endometrial Stromal Sarcoma, Endometrial Stromal

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (14)

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:15:47.114534+00:00
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