CDC42-positive macrophages may prevent malignant transformation of ovarian endometriosis

Belen Canet; Belén Canet; Cristina Pons; Inigo Espinosa; Íñigo Espinosa; Jaime Prat

doi:10.1016/j.humpath.2011.06.020

CDC42-positive macrophages may prevent malignant transformation of ovarian endometriosis

Belen Canet, Belén Canet, Cristina Pons, Inigo Espinosa, Íñigo Espinosa, Jaime Prat

Human pathology · 2011 · vol. 43(5) , pp. 720–725 · doi:10.1016/j.humpath.2011.06.020 · PMID:21944080 · W2087721739

article OA: closed CC0 ⤵ 7 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated how CDC42-positive macrophages influence the malignant transformation of ovarian endometriosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Carcinoma cdc42 GTP-Binding Protein Cell Transformation, Neoplastic Endometriosis Macrophages Ovarian Diseases Adult Carcinoma Carcinoma Carcinoma cdc42 GTP-Binding Protein cdc42 GTP-Binding Protein Cell Transformation, Neoplastic Cell Transformation, Neoplastic Cell Transformation, Neoplastic Endometriosis Endometriosis Endometriosis Female Humans

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References (35)

Altered gene expression and secretion of interleukin-6 in stromal cells derived from endometriotic tissues via openalex
ENDOMETRIAL CARCINOMA OF THE OVARY, ARISING IN ENDOMETRIAL TISSUE IN THAT ORGAN via openalex
Histologic Transformation of Benign Endometriosis to Early Epithelial Ovarian Cancer via openalex
<i>ARID1A</i> Mutations in Endometriosis-Associated Ovarian Carcinomas via openalex
IL-1 Induction of RANTES (Regulated upon Activation, Normal T Cell Expressed and Secreted) Chemokine Gene Expression in Endometriotic Stromal Cells Depends on a Nuclear Factor- B Site in the Proximal Promoter via openalex
Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary. via openalex
Macrophages Are Alternatively Activated in Patients with Endometriosis and Required for Growth and Vascularization of Lesions in a Mouse Model of Disease via openalex
Molecular genetic evidence that endometriosis is a precursor of ovarian cancer via openalex
Possible involvement of loss of heterozygosity in malignant transformation of ovarian endometriosis via openalex
Prevalence of Endometriosis in Ovarian Cancer via openalex
The risk of cancer and the role of parity among women with endometriosis via openalex
W2053023842 via openalex
W2058648826 via openalex
W2073252833 via openalex
W2101278668 via openalex
W2127979123 via openalex
W2133769266 via openalex
W2148020952 via openalex
W2161608856 via openalex
W2164950092 via openalex
W2792015608 via openalex
W4249033337 via openalex
W6638686170 via openalex
W6679193883 via openalex
W7036447705 via openalex
W1959606306 via openalex
W1984998182 via openalex
W1996213381 via openalex
W2002621545 via openalex
W2018798658 via openalex
W2020176932 via openalex
W2022041162 via openalex
W2050668117 via openalex
W2052247980 via openalex
W2052481226 via openalex

Cited by (7)

Source provenance

europepmc: last seen: 2026-06-04T01:30:01.192114+00:00
openalex: last seen: 2026-06-04T00:00:01.174412+00:00
pubmed: last seen: 2026-05-13T22:16:29.858026+00:00

License: CC0 · commercial use OK

[1] Altered gene expression and secretion of interleukin-6 in stromal cells derived from endometriotic tissues via openalex

[2] ENDOMETRIAL CARCINOMA OF THE OVARY, ARISING IN ENDOMETRIAL TISSUE IN THAT ORGAN via openalex

[3] Histologic Transformation of Benign Endometriosis to Early Epithelial Ovarian Cancer via openalex

[4] <i>ARID1A</i> Mutations in Endometriosis-Associated Ovarian Carcinomas via openalex

[5] IL-1 Induction of RANTES (Regulated upon Activation, Normal T Cell Expressed and Secreted) Chemokine Gene Expression in Endometriotic Stromal Cells Depends on a Nuclear Factor- B Site in the Proximal Promoter via openalex

[6] Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary. via openalex

[7] Macrophages Are Alternatively Activated in Patients with Endometriosis and Required for Growth and Vascularization of Lesions in a Mouse Model of Disease via openalex

[8] Molecular genetic evidence that endometriosis is a precursor of ovarian cancer via openalex

[9] Possible involvement of loss of heterozygosity in malignant transformation of ovarian endometriosis via openalex

[10] Prevalence of Endometriosis in Ovarian Cancer via openalex

[11] The risk of cancer and the role of parity among women with endometriosis via openalex

[12] W2053023842 via openalex

[13] W2058648826 via openalex

[14] W2073252833 via openalex

[15] W2101278668 via openalex

[16] W2127979123 via openalex

[17] W2133769266 via openalex

[18] W2148020952 via openalex

[19] W2161608856 via openalex

[20] W2164950092 via openalex

[21] W2792015608 via openalex

[22] W4249033337 via openalex

[23] W6638686170 via openalex

[24] W6679193883 via openalex

[25] W7036447705 via openalex

[26] W1959606306 via openalex

[27] W1984998182 via openalex

[28] W1996213381 via openalex

[29] W2002621545 via openalex

[30] W2018798658 via openalex

[31] W2020176932 via openalex

[32] W2022041162 via openalex

[33] W2050668117 via openalex

[34] W2052247980 via openalex

[35] W2052481226 via openalex