[The functional links in the neuroendocrine interrelationship in juvenile uterine hemorrhages]

A simultaneous and combined study of function of the neuroendocrine regulation of menstrual function in patients with juvenile uterine bleeding (JUB) (by the excretion of LH, noradrenalin, dopa and dopamine with urine and by the blood levels of TSH, T3, T4, ACTH and cortisol and by functional diagnostic tests) has shown that JUB is characterized by dysfunction of all important factors in this complex neuro-regulatory chain, resulting in disorder of hormonal homeostasis and pathological changes in the actuating organs. These changes are particularly marked and profound in JUB developing against a background of irregular menstrual function.