Rectal endometriosis mimicking solitary rectal ulcer syndrome

Daya D, D Daya, O'Connell G, G O'Connell, Graeme O’Connell, DeNardi F, F DeNardi, Franco DeNardi
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 1995 · vol. 8(6) , pp. 599–602 · PMID:8532690 · W2409590619
Case report OA: closed CC0 ⤵ 10 in-corpus citations
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This report details a case where rectal endometriosis mimicked solitary rectal ulcer syndrome and required multiple biopsies, aided by immunohistochemistry, to differentiate from colitis cystica profunda.

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Abstract

We report a unique case of rectal endometriosis mimicking solitary rectal ulcer syndrome. Several rectal biopsies were performed before the correct diagnosis of rectal endometriosis was made. The lesion had striking histologic features resembling colitis cystica profunda. The presence of two types of glands, i.e., colonic glands with marked depletion of mucin and endometrial glands, were readily apparent on immunohistochemical stain using anticarcinoembryonic antigen showing positive cytoplasmic stain for colonic glands but negative for endometrial glands. However, the distinction between colonic and endometrial glands was very difficult on hematoxylin-and-eosin-stained slides. Endometrial stroma was identified only in the sixth biopsy specimen. Although rare, rectal endometriosis should be considered in the differential diagnosis of solitary rectal ulcer syndrome.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Rectal Diseases Rectum Adult Adult Biopsy Biopsy Carcinoembryonic Antigen Carcinoembryonic Antigen Carcinoembryonic Antigen Colon Colon Colon Diagnosis, Differential Diagnosis, Differential Diagnostic Errors Diagnostic Errors Endometriosis Endometriosis Endometrium

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (10)

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europepmc
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License: CC0 · commercial use OK