Effects of estriol administration on human postmenopausal endometrium
Non-randomised trial
OA: closed
CC0
AI-generated summary
Oral estriol administration for 10 to 25 days induced endometrial hyperplasia in 70.8% of postmenopausal women with initially atrophic endometrium, while only 29.2% retained the atrophic state.
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Abstract
Forty eight women with atrophic endometrium were treated with estriol, 1 mg twice daily, by mouth for a minimum of 10 days and a maximum of 25 days. Vaginal hysterectomy was then performed and specimens were examined histologically. Results showed that estriol produces endometrial hyperplasia in 70.8% of the examined women; only 29.2% of the patients retained atrophic endometrium after treatment.
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:32:28.090074+00:00
License: CC0
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