Diagnostic value of structured anamnesis for phenotype identification in chronic pelvic pain syndrome: A practice-oriented retrospective study

E Vicente Palacio, Enoc Valentín González Palacio, P. Bosch Knape, S. Tarragón Gabarro, C. Centeno Álvarez, L. de Verdonces Román, A. Sanchez i Puy, B. Juaneda Castell, S. Cuadrench Solorzano, E Sotelo Burillo, Elena Burillo, L.M. Marco pérez, L Sabiote Rubio, Laia Sabiote Rubio, D Salinas Duffo, J A Peña González, Juan Ángel González
Actas urologicas espanolas · 2025 · vol. 49(9) , pp. 501858 · doi:10.1016/j.acuroe.2025.501858 · PMID:40947057 · W4414168043
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This study evaluated the effectiveness of structured anamnesis in identifying specific phenotypes within patients diagnosed with chronic pelvic pain syndrome.

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Abstract

OBJECTIVE: To assess whether chronic pelvic pain presents specific qualitative traits, as described by patients, that can guide identification of its underlying clinical phenotype. MATERIALS AND METHODS: A retrospective study including 157 patients (81 men, 76 women), interviewed systematically by a single evaluator using a structured 10-item table aimed at identifying three possible phenotypes. The correlation between the predicted phenotype (based solely on anamnesis) and the final phenotype (established through physical examination, treatment response, and clinical evolution) was analyzed. Sensitivity (Se), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV), and area under the curve (AUC) were calculated by phenotype and sex. The diagnostic relevance of each question was assessed, and statistical significance was tested using the Chi-square test. RESULTS: In women, the proportion of predicted phenotypes confirmed as final was: 64.5% bladder, 19.7% myofascial, 30.2% neuropathic. In men: 8.6% bladder, 81.5% myofascial, 23.5% neuropathic. Women-bladder: Se 0.92, Sp 0.74, PPV 0.90, NPV 0.72, AUC 0.82. Myofascial: Se 0.44, Sp 0.93, PPV 0.79, NPV 0.75, AUC 0.76. Neuropathic: Se 0.36, Sp 0.98, PPV 0.89, NPV 0.79, AUC 0.51. Men-bladder: Se 0.57, Sp 0.83, PPV 0.21, NPV 0.96, AUC 0.81. Myofascial: Se 0.75, Sp 0.75, PPV 0.93, NPV 0.41, AUC 0.75. Neuropathic: Se 0.29, Sp 1.00, PPV 1.00, NPV 0.80, AUC 0.64. CONCLUSIONS: A structured anamnesis may help identify the clinical phenotype underlying chronic pelvic pain (bladder, myofascial, or neuropathic).

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Condition tags

chronic_pelvic_pain

MeSH descriptors

Chronic Pain Chronic Pain Medical History Taking Pelvic Pain Pelvic Pain Pelvic Pain Adult Aged Female Humans Male Middle Aged Phenotype Retrospective Studies

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References (12)

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
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