[Catamenial epilepsy]

M Salvi, I Canova, S Caputo
La Clinica terapeutica · 2003 · vol. 154(2) , pp. 111–3 · PMID:12856370 · W4299914137
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This paper reviews the influence of ovarian steroid hormones on neuronal excitability and catamenial seizure fluctuations, highlighting the need to clarify etiology and establish optimal management strategies.

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Abstract

Many women with epilepsy report changes in seizures frequency in relationship to their menstrual cycle. Evidence from animal experiments and studies in humans have demonstrated an ovarian steroid hormone effect on neuronal excitability. The entity of the problem and its treatment have yet to be systematically evaluated. Is important to clarify the etiology and pathogenesis of catamenial fluctuations in seizure frequency and to outline optimal management strategies.

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MeSH descriptors

Epilepsy Menstrual Cycle Abnormalities, Drug-Induced Abnormalities, Drug-Induced Animals Anticonvulsants Anticonvulsants Anticonvulsants Biotransformation Biotransformation Contraindications Epilepsy Epilepsy Epilepsy Female Gonadal Steroid Hormones Gonadal Steroid Hormones Gonadal Steroid Hormones Hormone Antagonists Hormone Antagonists

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SciLite annotations

organisms 3
noordeloos 2009062 rodents humans

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License: CC0 · commercial use OK