Lumbocostovertebral syndrome with associated VACTERL anomaly

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This report describes the second case of lumbocostovertebral syndrome associated with VACTERL anomalies, presenting a male neonate with thoracic hemivertebrae, high anorectal malformation, dextrocardia, renal pyelectasis, hypospadias, and congenital talipes equinovarus.

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Abstract

Lumbocostovertebral syndrome is a rare clinical association syndrome rarely accompanied by associated VACTERL anomalies. Only one similar case has been reported previously. We describe the second case, where a male neonate born at 38 weeks of gestation had an unusually high number of congenital anomalies including thoracic hemivertebrae with kyphoscoliosis, a high anorectal malformation, dextrocardia with an atrial septal defect, renal pelvic pyelectasis, hypospadias, and congenital talipes equinovarus.

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MeSH descriptors

Abnormalities, Multiple Heart Defects, Congenital Heart Defects, Congenital Heart Defects, Congenital Limb Deformities, Congenital Limb Deformities, Congenital Limb Deformities, Congenital Anal Canal Anal Canal Anal Canal Esophagus Esophagus Esophagus Hernia Hernia Humans Infant, Newborn Kidney Kidney Kidney

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Source provenance

europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
pubmed
last seen: 2026-10-08T21:08:04.945943+00:00