Danazol treatment and platelet function
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⤵ 4 in-corpus citations
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Danazol treatment for endometriosis significantly increased platelet count in women, with minor release defects appearing in some but likely only clinically relevant in those with pre-existing platelet issues.
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Abstract
Platelet count and platelet function have been studied in detail in 14 women before and during treatment with danazol for endometriosis. A progressive and highly significant increase in platelet count was recorded from the pretreatment value (311 x 10(9)/L) to the value after six months of treatment (366 x 10(9)/L; P less than 0.001). Five patients developed minor platelet release defects, which may have been caused by the drug. However, the abnormalities shown are only likely to be of clinical importance in patients with preexisting platelet abnormalities.
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Too few in-corpus citations on either side for a chart; here are the lists.
Cites (2)
- The effect of danazol on menorrhagia, coagulation mechanisms, haematological indices and body weight 1979
- Danazol--a steroid with a unique combination of actions 1979
Cited by (4)
- Anti-platelet therapy holds promises in treating adenomyosis: experimental evidence 2016
- The Role of Platelets in the Pathogenesis and Pathophysiology of Adenomyosis 2023
- Hypercoagulability in women with adenomyosis who experience heavy menstrual bleeding 2023
- A Study on the Antithrombotic Effect of Danazol 1990
References (7)
- Danazol--a steroid with a unique combination of actions via openalex
- The effect of danazol on menorrhagia, coagulation mechanisms, haematological indices and body weight via openalex
- W2049803596 via openalex
- W3998058 via openalex
- W6717018785 via openalex
- W2061626350 via openalex
- W2034443296 via openalex
Cited by (4)
- Hypercoagulability in women with adenomyosis who experience heavy menstrual bleeding 2023
- The Role of Platelets in the Pathogenesis and Pathophysiology of Adenomyosis 2023
- Anti-platelet therapy holds promises in treating adenomyosis: experimental evidence 2016
- A Study on the Antithrombotic Effect of Danazol 1990
Source provenance
- europepmc
- last seen: 2026-10-13T06:10:10.580696+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-10-08T21:58:42.677500+00:00
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