[Vaginal adenosis: A case report and literature review]

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This case report describes vaginal adenosis in a 42-year-old woman, highlighting its rare nature and potential progression to adenocarcinoma in DES-exposed patients.

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Abstract

We report a case of vaginal adenosis in a woman of 42years. This is a rare congenital disorder since cessation of use of diethylstilbestrol (DES), usually of benign course, not to ignore in its tubo-endometrial histological form which may progress to atypical adenosis precursor of vaginal clear cell adenocarcinoma in patients exposed in utero to DES.

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MeSH descriptors

Exocrine Glands Vaginal Diseases Adult Adult Biopsy Biopsy Cell Differentiation Cell Differentiation Diagnosis, Differential Diagnosis, Differential Diethylstilbestrol Diethylstilbestrol Diethylstilbestrol Exocrine Glands Exocrine Glands Female Female Humans Humans Infertility, Female

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europepmc
last seen: 2026-10-25T09:32:14.900964+00:00
pubmed
last seen: 2026-10-08T21:18:17.876363+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine