Correlation between laparoscopic and histopathologic diagnosis of endometriosis

Sikolia Wanyonyi, Sikolia Z Wanyonyi, E Sequeira, Evan Sequeira, Samuel G Mukono
International Journal of Gynecology & Obstetrics · 2011 · vol. 115(3) , pp. 273–276 · doi:10.1016/j.ijgo.2011.07.022 · PMID:21944490 · W2007116712
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Abstract

OBJECTIVE: To review the histopathologic diagnosis of biopsies taken following visualization of endometriosis at laparoscopy and to correlate visual with microscopic diagnoses. METHODS: A retrospective review was undertaken of medical charts with a diagnosis of endometriosis at Aga Khan University Hospital, Nairobi, Kenya, between January 2001 and October 2010. Eligibility included visual diagnosis of endometriosis at laparoscopy, with a clear record of site, size, morphology, and number of lesions. The histopathologic diagnosis of the biopsies sampled was sought. Correlation was undertaken using κ statistics for diagnostic variability. RESULTS: Of the 204 relevant records, 152 (74.5%) met the eligibility criteria; from these cases, 239 specimens were submitted for histology. The most common symptom was chronic pelvic pain (108 [71.1%]). Most biopsies were obtained from the ovary and posterior cul-de-sac. Histopathologic diagnosis was confirmed in (152 [63.8%]) specimens and correlated with Asian race, multiparity, and chronic pelvic pain. Neither the site of the lesion nor the stage of disease influenced the histopathologic diagnosis. CONCLUSION: Laparoscopic visualization of endometriosis does not always correlate with histopathologic diagnosis; several other lesions may mimic endometriosis on histopathologic examination.

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Condition tags

mesh:D004715endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Laparoscopy Adolescent Adult Biopsy Endometriosis Endometriosis Female Humans Kenya Laparoscopy Middle Aged Ovary Ovary Retrospective Studies Young Adult

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