Role of EUS and EUS-guided FNA in the diagnosis of symptomatic rectosigmoid endometriosis

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This study evaluated the diagnostic utility of endoscopic ultrasound (EUS) and EUS-guided fine-needle aspiration (FNA) for rectosigmoid endometriosis in symptomatic patients.

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Abstract

BACKGROUND: Rectosigmoid endometriosis is an underrecognized cause of GI symptoms in women. Pelvic magnetic resonance imaging and CT have a low sensitivity in making this diagnosis. The role of EUS and EUS-guided FNA (EUS-FNA) in the diagnosis of rectosigmoid endometriosis in symptomatic patients is not well studied. METHODS: A review of medical records identified 5 women who were diagnosed with rectosigmoid endometriosis by EUS and EUS-FNA over a period of 1 year. OBSERVATIONS: Five women with nonspecific GI complaints underwent EUS examination of a rectosigmoid subepithelial mass found on colonoscopy. EUS revealed a hypoechoic lesion infiltrating the muscularis propria and the serosa of the rectal wall, and extending outside the rectal wall, findings consistent with rectosigmoid endometriosis. This diagnosis was confirmed by EUS-FNA, surgical exploration, and/or the patient's clinical course. CONCLUSIONS: EUS and EUS-FNA are noninvasive, sensitive techniques for the diagnosis of rectosigmoid endometriosis in symptomatic patients.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endosonography Endosonography Rectal Diseases Sigmoid Diseases Adult Adult Biopsy, Fine-Needle Biopsy, Fine-Needle Biopsy, Fine-Needle Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Endometriosis Female Female Humans Humans Middle Aged

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References (27)

Cited by (32)

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europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
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License: CC0 · commercial use OK