Malignant Transformation of Abdominal Wall Endometriosis to Clear Cell Carcinoma: A Case Report

This case report describes the rare malignant transformation of abdominal wall endometriosis into clear cell carcinoma in a patient with a history of prior surgeries. The authors detail the clinical presentation, histopathological analysis, and surgical management required to treat this specific complication arising from ectopic endometrial tissue. The paper highlights that while such malignancy is uncommon, it represents a serious long-term risk for patients with deep infiltrating or surgical site endometriosis who present with new or worsening masses. This paper is centrally about endometriosis — specifically the malignant degeneration of abdominal wall lesions into clear cell carcinoma.

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