SYNTHESIS OF 21-CHLORODANAZOL AND ITS △~6-ANALOGUE
Lab / animal
OA: closed
CC0
AI-generated summary
Researchers synthesized 21-chloro-danazol and its delta-6 analogue, finding they bound less effectively to progesterone receptors than danazol while the former terminated early pregnancy in rats.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Synthesis was undertaken of 21-chloro-danazol (Ⅳa) and 21-chloro-6-dehydro-danazol (Ⅳb). The binding ability of these compounds to progesterone receptor were examined and were found to be less active than danazol.Compound (Ⅳa) showed significant activity for eary pregnancy termination effect in Sprague-Dawley rats.
My notes (saved in your browser only)
Citation neighborhood (no data yet)
We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.
Source provenance
- openalex
- last seen: 2026-05-10T10:02:18.307429+00:00
License: CC0
· commercial use OK