A National Survey of Umbilical Endometriosis in Japan

Tetsuya Hirata, Hirata T, Kaori Koga, Kitade M, Mari Kitade, Shinya Fukuda, Fukuda S, Neriishi K, Kazuaki Neriishi, Taniguchi F, Fuminori Taniguchi, Ritsuo Honda, Honda R, Naoko Takazawa, Takazawa N, Toshiaki Tanaka, Tanaka T, Masatoshi Kurihara, Kurihara M, Jun Nakajima, Nakajima J, Horie S, Shigeo Horie, Nakai H, Hidekatsu Nakai, Enomoto T, Takayuki Enomoto, Mandai M, Masaki Mandai, Narahara H, Hisashi Narahara, Kitawaki J, Jo Kitawaki, Harada T, Tasuku Harada, Hidetaka Katabuchi, Katabuchi H, Kotaro Yoshimura, Osuga Y, Yutaka Osuga
Journal of Minimally Invasive Gynecology · 2019 · vol. 27(1) , pp. 80–87 · doi:10.1016/j.jmig.2019.02.021 · PMID:30965115 · W2932205255
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This paper presents findings from a national survey of umbilical endometriosis in Japan, detailing its prevalence and characteristics.

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Abstract

STUDY OBJECTIVE: To identify the clinical presentation, diagnostic evaluation, operative or medical management, and postoperative recurrence of umbilical endometriosis. DESIGN: A retrospective national survey. SETTING: Obstetrics and Gynecology and Plastic Surgery Departments at a teaching hospital in Japan. PATIENTS: Patients with umbilical endometriosis or malignant transformation. INTERVENTIONS: A national survey was conducted to identify and evaluate cases of umbilical endometriosis or malignant transformation documented between 2006 and 2016. MEASUREMENTS AND MAIN RESULTS: The following were evaluated for each patient: age at diagnosis, body mass index, medical history, presence of extragenital endometriosis, surgical history, symptoms, imaging modalities, surgical therapy, hormonal therapy, follow-up period, postoperative recurrence, and time to recurrence. Ninety-six patients were identified with pathologically diagnosed benign umbilical endometriosis. The patients frequently had swelling (86.5%), pain (81.3%), or bleeding (44.8%) in the umbilicus. Sensitivity was 87.1% for physical examination, 76.5% for transabdominal ultrasonography, 75.6% for computed tomography, and 81.8% for magnetic resonance imaging. The cumulative recurrence rate was 1.34% at 6 months, 6.35% at 12 months, and 6.35% at 60 months after surgery. Importantly, there was no recurrence after wide resection including of the peritoneum (0 of 37 cases). The efficacy of dienogest (an oral progestin), gonadotropin-releasing hormone agonists, and oral contraceptives was 91.7%, 81.8%, and 57.1%, respectively. Finally, 2 cases of malignant transformation were identified. CONCLUSION: There was a low recurrence rate following surgery, and hormonal treatment is an option, although the current findings suggest surgical therapy as the first choice of treatment for umbilical endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Muscular Diseases Muscular Diseases Umbilicus Adult Adult Endometriosis Endometriosis Female Female Humans Humans Japan Japan Japan Middle Aged Middle Aged Muscular Diseases Muscular Diseases

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