Doppler study of uterine hemodynamics in women with unexplained infertility

Akmal El-Mazny, Akmal El‐Mazny, Nermeen Abou-Salem, Nermeen Abou‐Salem, Hossam ElShenoufy
European journal of obstetrics, gynecology, and reproductive biology · 2013 · vol. 171(1) , pp. 84–87 · doi:10.1016/j.ejogrb.2013.08.026 · PMID:24011380 · W2039097889
Non-randomised trial OA: closed CC0 ⤵ 3 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-18 ⓘ

Doppler ultrasound revealed impaired endometrial perfusion in women with unexplained infertility, characterized by increased uterine artery resistance and decreased endometrial and subendometrial vascularization.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVE: To evaluate uterine artery blood flow using pulsed Doppler, and endometrial and subendometrial microvascularization using three-dimensional (3D) power Doppler, in women with unexplained infertility. STUDY DESIGN: In a prospective clinical trial at a university teaching hospital, 40 women with unexplained infertility were compared to 40 fertile parous controls. In the mid-luteal (peri-implantation) phase, the endometrial thickness and volume, uterine artery pulsatility index (PI) and resistance index (RI), endometrial and subendometrial 3D power Doppler vascularization index (VI), flow index (FI), and vascularization flow index (VFI), and serum estradiol and progesterone levels were measured in both groups. RESULTS: The uterine artery PI (P = 0.003) and RI (P = 0.007) were significantly increased and the endometrial VI (P = 0.029), FI (P = 0.031), and VFI (P = 0.001) and subendometrial VI (P = 0.032), FI (P = 0.040), and VFI (P = 0.005) were significantly decreased in the unexplained infertility group. The endometrial thickness and volume and serum estradiol and progesterone levels, however, were not significantly different between the two groups. CONCLUSION: Peri-implantation endometrial perfusion is impaired in women with unexplained infertility: Doppler study of uterine hemodynamics should therefore be considered in infertility work-up.

My notes (saved in your browser only)

Condition tags

infertility

MeSH descriptors

Endometrium Hemodynamics Infertility, Female Uterine Artery Uterus Adult Endometrium Endometrium Female Humans Infertility, Female Infertility, Female Prospective Studies Regional Blood Flow Ultrasonography, Doppler, Color Ultrasonography, Doppler, Color Uterine Artery Uterus Uterus Vascular Resistance

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (32)

Cited by (5)

Source provenance

openalex
last seen: 2026-05-11T06:15:24.675520+00:00
pubmed
last seen: 2026-10-08T21:12:29.265612+00:00
License: CC0 · commercial use OK