Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagia.
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Abstract
AIMS: To evaluate the efficacy, acceptability and side effects of levonorgestrel intrauterine system in patients with idiopathic menorrhagia. METHODS: A prospective, non-randomized clinical study in which 42 women between the age of 35-55 years complaining of menorrhagia with or without irregular cycle were recruited during one year period. The women were followed up at 3, 6, 12, 24 and 36 months after insertion. RESULTS: The reduction in mean blood loss was found to be statistically significant with a p value of < 0.001 for all the follow-up periods. CONCLUSION: The present study projects levonorgestrel intrauterine system as an effective patient friendly device with a high degree of compliance and worth considering as a viable alternative to surgery for the management of menorrhagia due to dysfunctional uterine bleeding in developing countries like India.
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Cites (3)
- The effects of the levonorgestrel intrauterine system (Mirena coil) on endometrial morphology 2003
- mRNA expression of insulin-like growth factor-I (IGF-I) is suppressed and those of IGF-II and IGF-binding protein-1 are constantly expressed in the endometrium during use of an intrauterine levonorgestrel system 1997
- Correlation between endometrial histology, microvascular density and calibre, matrix metalloproteinase-3 and bleeding pattern in women using a levonorgestrel-releasing intrauterine system 2004
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References (6)
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- mRNA expression of insulin-like growth factor-I (IGF-I) is suppressed and those of IGF-II and IGF-binding protein-1 are constantly expressed in the endometrium during use of an intrauterine levonorgestrel system via openalex
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