Complex Korean Medicine Therapy for Hypoestrogenic Side Effects of Gonadotropin Releasing Hormone Agonist Administration to Postoperative Endometriosis Patient: A Case Report

Hye-Rin Park, Hee-Geun Jo, Hyun-Jeong Jo, Jihyun Choi
In: The Journal of Korean Obstetrics and Gynecology · 2018 · vol. 31(4) , pp. 188–196 · doi:10.15204/jkobgy.2018.31.4.188 · W2959902294
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⚙ AI-generated summary by gemini-2.5-flash-lite+body, 2026-07-22 ⓘ

This case report details the positive effects of complex Korean medicine therapy on a postoperative endometriosis patient experiencing hypoestrogenic side effects from GnRH-agonist treatment, improving symptoms and quality of life.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-28 · read from full text ⓘ

This case report examines the clinical effectiveness of complex Korean medicine therapy in managing hypoestrogenic side effects, such as hot flashes and sweating, in a patient undergoing GnRH-agonist treatment for postoperative endometriosis. The study involved a single patient who received ten days of specialized Korean medicine therapy following laparoscopic surgery, with outcomes assessed using the Kupperman’s Index and SF-36 health survey. Results indicated significant improvement in vasomotor symptoms and an overall enhancement in the patient's quality of life after the intervention. Relevance to endometriosis: This paper is centrally about endometriosis, specifically focusing on the management of side effects from standard hormonal treatments used in postoperative care.

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초록 열기/닫기 버튼 Objectives: This study is to report the clinical effectiveness of the complex Korean medicine therapy on a postoperative endometriosis patient’s hypoestrogenic side effects who is treated with GnRH-agonist injection. Methods: The patient in this case was diagnosed with endometriosis and has been treated with GnRH-a injection after laparoscopic operation. The patient complained hot flash and sweating mainly after GnRH-a treatment. The patient received complex Korean medicine therapy during 10 days admission period. The clinical effects were evaluated through KI (Kupperman’s Index) and SF-36 (36 item Short Form Health Survey). Results: After the complex Korean medicine therapy, the various clinical symptoms including hot flash and sweating were improved. Also, the quality of life was enhanced. Conclusions: This case report shows that the complex Korean medicine therapy was effective for treating hypoestrogenic side effects occurred after GnRH-a treatment in postoperative endometriosis patient.

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endometriosis

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