[Steroid treatment of adolescent gynecomastia with danazol (author's transl)]
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Danazol, a synthetic steroid, successfully reduced breast tissue in 15 male adolescents with pubertal gynecomastia, showing rare and negligible side effects.
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Abstract
Report on the successful treatment of pubertal gynecomastia with the synthetic steroid preparation Danazol. In 15 male adolescents, 11 to 18 years old, Danazol in an average dose of 8 to 10 mg/kg/day, administered orally over 2 to 3 months, achieved a very good or good reduction of breast tissue. 4 patients showed a palpable but insufficient regression. Side-effects of the treatment were rare and clinically negligible. The mechanism of the hormonal action of the gonadotropin inhibiting steroid Danazol in gynecomastia cannot be explained by the hormone findings available so far.
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- openalex
- last seen: 2026-05-10T10:46:18.646890+00:00
- pubmed
- last seen: 2026-10-08T21:58:37.372514+00:00
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