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Prediction of possibility of non-IVF pregnancy after laparoscopic surgery in infertile women with endometriosis using Endometriosis Fertility Index
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- HORIE Akihito
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
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- OKUNOMIYA Asuka
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
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- BABA Tsukasa
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
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- ABIKO Kaoru
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
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- YAMAGUCHI Ken
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
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- MATSUMURA Noriomi
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
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- SATO Yukiyasu
- Department of Obstetrics and Gynecology, Otsu Red Cross Hospital
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- KONISHI Ikuo
- Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine
Bibliographic Information
- Other Title
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- 子宮内膜症合併不妊女性に対する腹腔鏡手術後の自然妊娠の可能性をEndometriosis Fertility Indexで予測できるか
- シキュウ ナイマクショウ ガッペイ フニン ジョセイ ニ タイスル フククウキョウ シュジュツゴ ノ シゼン ニンシン ノ カノウセイ オ Endometriosis Fertility Index デ ヨソク デキル カ
- Published
- 2015
- DOI
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- 10.11437/sanpunosinpo.67.264
- Publisher
- THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN
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Description
Objective) Laparoscopic surgery is one of the treatment options for infertile endometriotic women. Although the revised American Fertility Society score (rAFS score) has been widely used to indicate the severity of endometriosis, it is difficult to predict the possibility of postoperative pregnancy using it. Recently, the Endometriosis Fertility Index (EFI) was proposed as a scoring system useful for predicting the possibility of non-IVF pregnancy after the surgery. Nevertheless, it remains unclear whether EFI is similarly useful in Japanese women. Therefore, in this study, we evaluated the usefulness of EFI in Japanese patients. Method) We enrolled 57 infertile endometriotic patients who underwent laparoscopic surgery followed by non-IVF treatment at Kyoto University Hospital between January 1999 and May 2012. Firstly, the EFI and rAFS score were compared between the pregnancy (n=35) and non-pregnancy (n=22) groups. Next, cumulative pregnancy rates in the EFI≦6 group and EFI≧7 group were compared using the Kaplan-Meier method. Finally, multivariate analysis was conducted to assess the correlation between pregnancy and each component of the EFI. Results) The EFIs in the non-pregnancy group was significantly lower than that in the pregnancy group (mean±SD: 5.68±1.42 vs. 6.86±1.42, respectively). On the other hand, the difference did not reach significance for rAFS scores. The cumulative pregnancy rate in the EFI≦6 group was significantly lower than that in the EFI≧7 group. On multivariate analysis of the EFI, the strongest (but not significant) correlation was observed for the age of patents. Subgroup analysis of patients aged 35 years or younger showed that the EFI of the non-pregnancy group was significantly lower than that of the pregnancy group. In contrast, no difference was observed in the patients aged 36 years or older. Conclusion) The EFI but not rAFS score was correlated with the possibility of postoperative non-IVF pregnancy in endometriotic Japanese women. EFI≦6 could be considered as a low pregnancy potential. The EFI might be useful to select patients who require an early treatment step-up to IVF after surgery for endometriosis. [Adv Obstet Gynecol, 67 (3) : 264-269, 2015 (H27.8)]
Journal
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- ADVANCES IN OBSTETRICS AND GYNECOLOGY
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ADVANCES IN OBSTETRICS AND GYNECOLOGY 67 (3), 264-269, 2015
THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN
Keywords
Details 詳細情報について
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- CRID
- 1390282679922997504
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- NII Article ID
- 130005101920
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- NII Book ID
- AN00099490
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- ISSN
- 13476742
- 03708446
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- NDL BIB ID
- 026649526
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- CiNii Articles
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- Abstract License Flag
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