Antimüllerian hormone and pituitary gland activity after prolonged down-regulation with goserelin acetate
Non-randomised trial
OA: closed
public-domain-us
AI-generated summary
Prolonged goserelin acetate treatment maintained normal AMH levels but profoundly suppressed LH, suggesting the need for exogenous LH or GnRH agonist administration for IVF.
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Abstract
The size of the pool of growing follicles was normal after prolonged down-regulation, as indicated by normal AMH levels 4 and 8 weeks after goserelin administration. However, there was a profound down-regulation of LH levels; therefore we suggest administration of exogenous LH to proceed to IVF or alternatively stimulation of endogenous LH secretion with daily administration of GnRH agonist. These need to be assessed prospectively.
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- europepmc
- last seen: 2026-11-08T09:52:27.483963+00:00
- pubmed
- last seen: 2026-10-08T21:03:58.311020+00:00
- unpaywall
- last seen: 2026-11-03T06:29:01.780496+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine