Laparoscopic nerve lysis for deep endometriosis improves quality of life and chronic pain levels: A pilot study

Shlomo B Cohen, Yohann Dabi, Yechiel Z. Burke, Yechiel Burke, Nicole Mamadov, Nir Manoim, R. Mashiach, Roy Mashiach, Elad Berkowitz, Jerome Bouaziz, Jérôme Bouaziz, Alba Nicolás‐Boluda, Alba Nicolas-Boluda, Maria Grazia Porpora, Tomer Ziv‐Baran, Tomer Ziv-Baran
Journal of gynecology obstetrics and human reproduction · 2024 · vol. 53(7) , pp. 102778 · doi:10.1016/j.jogoh.2024.102778 · PMID:38570115 · W4393385454
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Laparoscopic neurolysis for endometriosis infiltrating pelvic nerves significantly improved chronic pain and quality of life in patients.

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Abstract

OBJECTIVES: To assess the benefit of surgical management of patients with endometriosis infiltrating pelvic nerves in terms of pain, analgesic consumption, and quality of life (QOL). METHODS: We conducted a retrospective cohort study In an Endometriosis referral center at a tertiary care university affiliated medical center. Patients diagnosed with endometriosis that underwent laparoscopic neurolysis for chronic pain were included. Patients rated their pain before and after surgery and differentiated between chronic pain and acute crises. Patients were requested to maintain a record of analgesic consumption and to evaluate their quality-of-life (QOL). RESULTS: Of the 21 patients in our study 15 (71.5 %) had obturator nerve involvement, 2 (9.5 %) had pudendal nerve involvement and 4 (19 %) had other pelvic nerve involvement. Median postoperative follow - up was of 8 months. All but 2 patients (9.6 %) had significant chronic pain improvement with a mean decrease of VAS of 3.05 (±2.5). Analgesic habits changed postoperatively with a significant decrease of 66 % of patients' daily consumption of any analgesics. Surgery improved QOL in 12 cases (57.1 %) and two patients (9.6 %) completely recovered with a high QOL. CONCLUSION: Neurolysis and excision of endometriosis of pelvic nerves could results in significant improvement of quality of life.

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Outcome instruments

VAS-pain

Condition tags

mesh:D004715mesh:D017699endometriosis

MeSH descriptors

Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Chronic Pain Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (36)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
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License: CC0 · commercial use OK