Comparison of degree of sexual dysfunction by using female sexual functional index-6 in the subfertile and other females presenting to tertiary care hospital
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by gemini-2.5-flash-lite, 2026-07-15
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Subfertile females exhibited significantly lower sexual function scores than a control group, indicating a higher prevalence of sexual dysfunction in this population.
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by claude@2026-06, 2026-06-15
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This cross-sectional prospective comparative study (Feb–July 2023) evaluated 276 sexually active Pakistani women aged 18–40 from a tertiary care hospital setting, comparing subfertile women with a non-subfertile group using a translated modified Female Sexual Functional Index Score limited to 6 items spanning desire, arousal, lubrication, orgasm, satisfaction, and pain. The key finding was that sexual dysfunction scores differed significantly between groups, with lower mean scores in the subfertile group (17.53±2.98) versus controls (20.4±3.26; p<0.001), and a cutoff of <19 indicating sexual dysfunction; the paper also reported that women with endometriosis had a lower mean score (15.91±3.4) than those without. The authors additionally stated the translated modified tool showed validity with moderate reliability for assessing sexual dysfunction in this population. Relevance to endometriosis: the paper reports subgroup results in women with endometriosis (mean sexual dysfunction score 15.91±3.4), though the study’s main focus is comparison of sexual dysfunction between subfertile and other women and validation of the modified FSFI-6.
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Abstract
OBJECTIVES: To compare the prevalence of sexual dysfunction between subfertile females and the general population, and to check the validity of the translated modified version of the Female Sexual Functional Index Score in Pakistani population.
METHODS: The cross-sectional, prospective, comparative, analytical study was conducted from February to July 2023 at the Shifa College of Medicine Hospital and the Kahuta Research Laboratories Hospital, Islamabad, and comprised females aged 18-40 years who had been sexually active for at least 4 preceding weeks. Subfertile women were placed in group A, while group B had normal women. Data was collected using the translated version of the Female Sexual Functional Index Score, limited to only 6 of the total 19 questions (Nos 2, 4, 7, 11, 16 and 17) to assess the female sexual dysfunction covering all the six domains of desire, arousal, lubrication, orgasm, satisfaction and pain. The total score ranged 2-30, with lower scores indicating worse sexual function. The cutoff point was 19, with <19 considered an indication of sexual dysfunction. Data was analysed using SPSS 23.
RESULTS: Of the 276 patients, 138(50%) were in each of the two groups. The overall mean age was 31.5±4.1 years. Mean score was 19±3.4. There was a significant difference in the scores between groups A 17.53±2.98 and B 20.4±3.26 (p<0.001). Patients with polycystic ovary syndrome had a higher mean score of 18.47±2.4, while those with endometriosis had mean score 15.91±3.4.
CONCLUSIONS: The prevalence of sexual dysfunction in the subfertile group was noted. The translated modified version of the Female Sexual Functional Index Score was found to be a valid tool with moderate reliability for the assessment of sexual dysfunction in Pakistani women.
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Objectives
To compare the prevalence of sexual dysfunction between subfertile females and the general population, and to check the validity of the translated modified version of the Female Sexual Functional Index Score in Pakistani population.
Method
The cross-sectional, prospective, comparative, analytical study was conducted February to July 2023 at the Shifa College of Medicine Hospital and the Kahuta Research Laboratories Hospital, Islamabad, and comprised females aged 18-40 years who had been sexually active for at least 4 preceding weeks. Subfertile women were placed in group A, while group B had normal women. Data was collected using the translated version of the Female Sexual Functional Index Score, limited to only 6 of the total 19 questions (Nos 2, 4, 7, 11, 16 and 17) to assess the female sexual dysfunction covering all the six domains of desire, arousal, lubrication, orgasm, satisfaction and pain. The total score ranged 2-30, with lower scores indicating worse sexual function. The cutoff point was 19, with <19 considered an indication of sexual dysfunction. Data was analysed using SPSS 23.
Results
Of the 276 patients, 138(50%) were in each of the two groups. The overall mean age was 31.5±4.1 years. Mean score was 19±3.4. There was a significant difference in the scores between groups A 17.53±2.98 and B 20.4±3.26 (p<0.001). Patients with polycystic ovary syndrome had a higher mean score of 18.47±2.4, while those with endometriosis had mean score 15.91±3.4.
Conclusion
The prevalence of sexual dysfunction in the subfertile group was noted. The translated modified version of the Female Sexual Functional Index Score was fund to be a valid tool with moderate reliability for the assessment of sexual dysfunction in Pakistani women.
Key Words: Infertility, Sexual satisfaction, Sexual dysfunction.
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Copyright (c) 2025 Journal of the Pakistan Medical Association
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