The clinical impact of in-vitro fertilization. Part 1. Results and limitations of conventional reproductive medicine

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This article examines the causes of infertility and the outcomes of conventional treatment for couples with single-cause infertility, while explaining the limitations when treating multiple or unexplained causes.

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Abstract

Conception is a matter of chance. A couple's monthly probability of conceiving naturally is known as their fecundability. The average "normal" fecundability (as a proportion) is approximately 0.2. This means that most young couples can expect to have children and will conceive within 12 months of attempting pregnancy. This article examines the causes of infertility and the results that can be achieved by conventional treatment among couples with a single cause for their infertility. The difficulties that are faced when conventional infertility treatment is applied to infertility with multiple causes or with no apparent cause are explained.

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Condition tags

endometriosisinfertility

MeSH descriptors

Fertilization in Vitro Fertilization in Vitro Infertility Adult Adult Endometriosis Endometriosis Endometriosis Fallopian Tube Diseases Fallopian Tube Diseases Fallopian Tube Diseases Female Female Fertility Fertility Humans Humans Infertility Infertility Infertility

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Source provenance

europepmc
last seen: 2026-11-08T09:52:27.483963+00:00
pubmed
last seen: 2026-10-08T21:35:21.651024+00:00
unpaywall
last seen: 2026-11-09T06:31:04.326590+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine