Long-term Quality of Life after Uterine Artery Embolization in Women with Adenomyosis and Fibroids versus Women with Fibroids Alone

Martin Popovic, Dominik Berzaczy, Stephan Puchner, Johannes Lämmer, RA Bucek
In: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2010 · vol. 182(S 01) · doi:10.1055/s-0030-1252810 · W1987520911
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A retrospective cohort study found that uterine artery embolization significantly improves long-term quality of life and reduces bleeding and pain symptoms in women with adenomyosis and fibroids compared to those with fibroids alone.

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This retrospective cohort study evaluated long-term quality of life in 72 women undergoing uterine artery embolization for either adenomyosis with fibroids or fibroids alone. Over a median follow-up of 6.8 years, patients in both groups experienced significant reductions in bleeding and pain scores, along with substantial improvements in general quality of life indices. The findings indicate that the procedure provides notable long-term symptomatic relief and quality of life enhancement for women with adenomyosis co-occurring with leiomyomata. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

Ziele: Assessment of long-term quality of life (QoL) in patients treated by uterine artery embolization (UAE) for either adenomyosis with fibroids (group 1) or patients with fibroids alone (group 2). Methode: 72 patients were included in this retrospective cohort study. Analysis was performed by a questionnaire consisting of 49 questions across six topics. Assessment focus was put on comparing symptoms and QoL in the long-term follow-up between the two study groups. Ergebnis: The median follow-up was 6.8 years (IQR: 5.2 years). 19 women were in group 1 and 53 women were in group 2. In comparing the two groups, UAE led to a reduction of the following symptoms: bleeding in 83.3% in group 1 and 71.4% in group 2, pain in 58.3% and 69.6%, bulk-related symptoms in 40.0% and 55.6%, respectively. The median impairment scores for bleeding decreased significantly from 7.0 to 0.0 and from 6.0 to 0.0 for groups 1 and 2, respectively (both p<0.001). Similar results were observed for median pain scores for group 1 and 2 (5.0 to 0.0 and 2.0 to 0.0, both p<0.001). The general QoL index increased significantly from 5.0 to 9.0 for group 1 and from 6.0 to 9.0 for group 2 (p<0.001). Schlussfolgerung: UAE seems to lead to a notable long-term improvement in QoL in patients suffering from both (adenomyosis and leiomyomata) and from fibroids alone.
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Subscribe to RSS DOI: 10.1055/s-0030-1252810 Long-term Quality of Life after Uterine Artery Embolization in Women with Adenomyosis and Fibroids versus Women with Fibroids Alone Ziele: Assessment of long-term quality of life (QoL) in patients treated by uterine artery embolization (UAE) for either adenomyosis with fibroids (group 1) or patients with fibroids alone (group 2). Methode: 72 patients were included in this retrospective cohort study. Analysis was performed by a questionnaire consisting of 49 questions across six topics. Assessment focus was put on comparing symptoms and QoL in the long-term follow-up between the two study groups. Ergebnis: The median follow-up was 6.8 years (IQR: 5.2 years). 19 women were in group 1 and 53 women were in group 2. In comparing the two groups, UAE led to a reduction of the following symptoms: bleeding in 83.3% in group 1 and 71.4% in group 2, pain in 58.3% and 69.6%, bulk-related symptoms in 40.0% and 55.6%, respectively. The median impairment scores for bleeding decreased significantly from 7.0 to 0.0 and from 6.0 to 0.0 for groups 1 and 2, respectively (both p<0.001). Similar results were observed for median pain scores for group 1 and 2 (5.0 to 0.0 and 2.0 to 0.0, both p<0.001). The general QoL index increased significantly from 5.0 to 9.0 for group 1 and from 6.0 to 9.0 for group 2 (p<0.001). Schlussfolgerung: UAE seems to lead to a notable long-term improvement in QoL in patients suffering from both (adenomyosis and leiomyomata) and from fibroids alone. Korrespondierender Autor: Popovic M Medizinische Universität Wien, Radiodiagnostik, Kardiovaskuläre und Interventionelle Radiologie, Währinger Gürtel 18–20, 1090, Wien E-Mail: [email protected] Leiomyomata - Adenomyosis - Uterine Artery Embolization

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