Highly-sensitive troponin I is increased in patients with gynecological cancers

Elisa Danese, Montagnana M, Martina Montagnana, Silvia Giudici, Giudici S, Silvia Dei Giudici, Aloe R, Rosalia Aloe, Massimo Franchi, Massimo Piergiuseppe Franchi, Gian Cesare Guidi, Giuseppe Lippi
Clinical biochemistry · 2013 · vol. 46(12) , pp. 1135–1138 · doi:10.1016/j.clinbiochem.2013.04.029 · PMID:23660299 · W2015008052
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This study investigated elevated levels of highly-sensitive troponin I in patients diagnosed with gynecological cancers.

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Abstract

OBJECTIVES: To investigate troponin I (TnI) in patients with gynecological cancers. METHODS: Highly-sensitive (HS) and conventional TnI were measured in 25 patients with untreated ovarian cancer, 25 with endometriosis and 25 with benign masses. RESULTS: Both HS and conventional TnI were increase in cancer patients. Values above the cut-off were found in 44% and 16% cancer patients using HS and conventional TnI methods, respectively. CONCLUSIONS: Cardiac involvement is frequent in patients with gynecological cancers and should be preferably assessed using HS troponin immunoassays.

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MeSH descriptors

Genital Neoplasms, Female Immunoassay Troponin I Adult Adult Female Female Genital Neoplasms, Female Genital Neoplasms, Female Humans Humans Immunoassay Immunoassay Middle Aged Middle Aged Sensitivity and Specificity Sensitivity and Specificity Troponin I Troponin I

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