[The natural cellular cytotoxicity of endometriosis patients]

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Natural killer cell activity remained stable throughout the menstrual cycle, but natural cellular cytotoxicity decreased in endometriosis patients, correlating with endocrine disease severity.

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Abstract

In the cytotoxic test, the level of natural cellular cytotoxicity (NCC) and activity of natural killers (NK) was determined in 16 patients with genital endometriosis and 36 healthy women in the time-course of a menstrual cycle. During the menstrual cycle, no substantial variations in NK activity were found in the healthy women and patients with endometriosis. There was a decrease in NCC only in patients with internal endometriosis, which correlated with severity of endocrine diseases.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Genital Neoplasms, Female Killer Cells, Natural Adult Adult Cytotoxicity Tests, Immunologic Cytotoxicity Tests, Immunologic Endometriosis Endometriosis Female Female Genital Neoplasms, Female Genital Neoplasms, Female Humans Humans Killer Cells, Natural Killer Cells, Natural Menstrual Cycle Menstrual Cycle Menstrual Cycle

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Source provenance

europepmc
last seen: 2026-10-20T06:13:28.455750+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:15:47.164179+00:00
License: CC0 · commercial use OK