Differences in clinical characteristics for the determination of adenomyosis coexisting with leiomyomas

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Women with both adenomyosis and leiomyomas, compared to leiomyoma-only patients, had higher gravidity, more frequent pelvic pain, and more postmenopausal bleeding.

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Abstract

AIM: The objective of the analysis was to determine the characteristics that distinguish women with adenomyosis and leiomyomas from those with leiomyoma only from a sample who underwent hysterectomy for benign uterine diseases. METHODS: This retrospective study was based on the analysis of medical records of 75 women with both adenomyosis and uterine leiomyomas and 218 women with leiomyomas only, diagnosed by histologic analysis of uterine specimens. RESULTS: Results of multivariate logistic regression analyses showed that women with both adenomyosis and leiomyomas had a higher gravity (odds ratio [OR] 1.16, 95% confidence interval [CI] 1.01-1.33) and more frequent pelvic pain (OR 0.38, 95% CI 0.21-0.7) compared with women with leiomyomas only. Postmenopausal bleeding was commonly reported in women with adenomyosis and leiomyomas. No significant difference was observed between the two groups in terms of menorrhagia and metrorrhagia and the preoperative diagnosis of prolapse. CONCLUSIONS: The presence of concomitant adenomyosis may cause different clinical symptomatology.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Leiomyoma Uterine Neoplasms Adenomyosis Adenomyosis Adult Comorbidity Female Humans Leiomyoma Leiomyoma Middle Aged Retrospective Studies Uterine Neoplasms Uterine Neoplasms

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
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