A Mini Review on Exosomal Mediators in Endometriosis: From Pathogenesis to Diagnostic and Therapeutic Avenues

Melika Izadpanah
In: Journal of Ardabil University of Medical Sciences · 2024 · vol. 24(2) , pp. 147–159 · doi:10.61186/jarums.24.2.147 · W4406395911
review OA: hybrid CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review explores the role of exosomes in endometriosis pathogenesis, highlighting their potential as diagnostic biomarkers and therapeutic targets due to their influence on angiogenesis, fibrosis, and inflammation.

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Abstract

Endometriosis is a long-term health condition that is known as a significant factor in women's infertility issues nowadays.Since many factors contribute to the development of this disease and because diagnosis is difficult and typically happens late in the progression of the disease, early detection is especially crucial.Extracellular micro vesicles called exosomes have diverse biological molecules and can alter the behavior of recipient cells, influencing angiogenesis, fibrosis, and inflammation.Exosomes are significant in cell communication and could act as new biomarkers for early detection of endometriosis.Hence, exploring and comprehending the impact of exosomes on the development of endometriosis can create opportunities for studying potential diagnostic biomarkers and targeted therapeutic interventions to prevent the advancement of the condition.This article delves into new approaches to diagnose and treat endometrial disorders by highlighting the various functions of exosomes in endometriosis.

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Condition tags

endometriosisinfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (45)

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last seen: 2026-06-04T00:00:01.174412+00:00
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