Loss of HDAC3 results in nonreceptive endometrium and female infertility

Tae Hoon Kim, Jung‐Yoon Yoo, Kyung‐Chul Choi, Jung‐Ho Shin, Richard E Leach, Asgerally T Fazleabas, Steven L. Young, Bruce A Lessey, Ho‐Geun Yoon, Jae‐Wook Jeong
Science translational medicine · 2019 · vol. 11(474) · doi:10.1126/scitranslmed.aaf7533 · PMID:30626716 · W2910914574
article OA: green CC0 ⤵ 60 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Loss of HDAC3 in mice disrupts endometrial receptivity and decidualization, leading to female infertility.

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Abstract

genes in humans. Our results suggest that HDAC3 is critical for endometrial receptivity and decidualization.

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Condition tags

mesh:D004715infertility

MeSH descriptors

Endometrium Endometrium Histone Deacetylases Infertility, Female Infertility, Female Adolescent Adult Animals Collagen Collagen Collagen Decidua Decidua Embryo Implantation Endometriosis Endometriosis Endometriosis Endometrium Female Histone Deacetylase 3

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (53)

Cited by (50)

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europepmc
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