Hernia sacs: is histological examination necessary?

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-12 ⓘ

Histological examination of abdominal and femoral hernia sacs is recommended due to unexpected diagnoses, while inguinal hernia histology can be left to pathologist discretion after gross examination.

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Abstract

The hernia sac is a common surgical pathology specimen which can occasionally yield unexpected diagnoses. The College of American Pathologists recommends microscopic examination of abdominal hernias, but leaves submission of inguinal hernias for histology to the discretion of the pathologist. To validate this approach at a tertiary care centre, we retrospectively reviewed 1426 hernia sacs derived from inguinal, femoral and abdominal wall hernias. The majority of pathologies noted were known to the clinician, including herniated bowel, lipomas and omentum. A malignancy was noted in three of 800 inguinal hernias and seven of 576 abdominal wall hernias; five of these lesions were not seen on gross examination. Other interesting findings in hernia sacs included appendices, endometriosis, a perivascular epithelioid cell tumour, and pseudomyxoma peritoneii. All hernia sacs should be examined grossly as most pathologies are grossly visible. The decision to submit inguinal hernias for histology may be left to the discretion of the pathologist, but abdominal and femoral hernias should be submitted for histology.

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Condition tags

endometriosis

MeSH descriptors

Hernia, Abdominal Abdominal Neoplasms Abdominal Neoplasms Abdominal Neoplasms Aged Aged Aged, 80 and over Aged, 80 and over Appendicitis Appendicitis Appendicitis Endometriosis Endometriosis Endometriosis Female Female Hernia, Abdominal Hernia, Abdominal Hernia, Abdominal Hernia, Abdominal

Citation neighborhood (sparse)

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Source provenance

europepmc
last seen: 2026-10-23T06:08:06.940705+00:00
pubmed
last seen: 2026-10-08T21:12:08.185882+00:00
unpaywall
last seen: 2026-10-23T06:24:35.503409+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine