Fallopian tube and endometriosis : an ambiguous relationship

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This review analyzes the effect of tubal endometriosis on fertility, noting that while moderate to severe disease impairs reproduction, the role of minimal lesions remains controversial despite evidence that tubal pathologies influence fertility in these patients.

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This review article examines the complex relationship between fallopian tube pathology and endometriosis, focusing on how tubal alterations may contribute to infertility in affected women. The authors note that while moderate to severe endometriosis clearly impacts fertility through adhesions, the role of minimal or mild lesions remains controversial despite their high prevalence in infertile populations. The paper highlights that tubal pathologies significantly influence fertility outcomes for these patients, though specific mechanistic details are debated in the literature. This paper is centrally about endometriosis — specifically analyzing the impact of tubal endometriosis on female fertility.

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Abstract

The Fallopian tube, or oviduct, plays an essential role in mammalian reproduction. Endometriosis affects 2 to 10% of women of reproductive age. Infertility and nulliparity are regarded as risk factors for endometriosis, therefore an increased prevalence of this affliction in the population of infertile women may be expected. The literature shows that endometriosis affects 30% to 68% of infertile women. However, its prevalence varies considerably depending on the type of infertility (i.e. male or female), the presence of chronic pelvic pain, and whether or not a previous exploratory laparoscopy was performed. The effects of endometriosis on fertility are still debated. While the impact of moderate or severe endometriosis on fertility is well established, especially in the presence of adhesions, the role of minimal or mild lesions, which are the most common in infertile women, is still controversial. Therefore, different possible underlying mechanisms have been proposed, including tubal alterations associated with endometriosis. Conclusion: Tubal pathologies have an influence on fertility in these patients. This short review analyzes the effect of tubal endometriosis on fertility.
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Keywords

Oviduct; tubal endometriosis; infertility; etiopathogenesis.

Abstract

[en] The Fallopian tube, or oviduct, plays an essential role in mammalian reproduction. Endometriosis affects 2 to 10% of women of reproductive age. Infertility and nulliparity are regarded as risk factors for endometriosis, therefore an increased prevalence of this affliction in the population of infertile women may be expected. The literature shows that endometriosis affects 30% to 68% of infertile women. However, its prevalence varies considerably depending on the type of infertility (i.e. male or female), the presence of chronic pelvic pain, and whether or not a previous exploratory laparoscopy was performed. The effects of endometriosis on fertility are still debated. While the impact of moderate or severe endometriosis on fertility is well established, especially in the presence of adhesions, the role of minimal or mild lesions, which are the most common in infertile women, is still controversial. Therefore, different possible underlying mechanisms have been proposed, including tubal alterations associated with endometriosis.

Conclusion

Tubal pathologies have an influence on fertility in these patients. This short review analyzes the effect of tubal endometriosis on fertility. Disciplines : Reproductive medicine (gynecology, andrology, obstetrics) Audebert, Alain TIMMERMANS, Marie ; Centre Hospitalier Universitaire de Liège - CHU > Département de gynécologie-obstétrique > Unité de recherche clinique (URC) Lismonde, Aurore BRICHANT, Géraldine ; Centre Hospitalier Universitaire de Liège - CHU > Département de gynécologie-obstétrique > Service de gynécologie-obstétrique (CHR) Nisolle, Michelle ; Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique Language : English Title : Fallopian tube and endometriosis : an ambiguous relationship Publication date : 2019 Journal title : European Gynecology and Obstetrics Volume : 1 Issue : 1 Pages : 18-23 Available on ORBi : since 30 November 2019

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Condition tags

endometriosischronic_pelvic_paininfertility

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