CORRELATION BETWEEN THE STATE OF GROWTH OF THE HUMAN ENDOMETRIUM AND ITS RESPONSE TO A SYNTHETIC PROGESTAGEN (CHLORMADINONE)

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⚙ AI-generated summary by qwen3.7-flash, 2026-10-10 ⓘ

This study investigated the effects of chlormadinone combined with estrogen on the uterine endometrium in menstruating and postmenopausal women, finding that the drug's impact is determined by the initial proliferative state of the tissue.

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Abstract

Summary. Chlormadinone, an orally active progestagen, was administered in conjunction with an oestrogen to normally menstruating and to postmenopausal women, and the changes induced in the uterine endometrium are described. The effects are not governed solely by the nature of the progestagen, but are directly related to the proliferative state of the endometrium at the start of treatment.

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MeSH descriptors

Chlormadinone Acetate Endometrium Histology Menopause Menstruation Mestranol Pharmacology Progesterone Congeners Progestins Female Humans

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:01:56.755204+00:00
unpaywall
last seen: 2026-11-01T06:18:20.579057+00:00
License: CC0 · commercial use OK