Haben orale Kontrazeptiva einen Stellenwert für die Prophylaxe und Therapie der Endometriose?

Karl-Werner Schweppe, Andreas D. Ebert
In: Geburtshilfe und Frauenheilkunde · 2020 · vol. 80(07) , pp. 672–674 · doi:10.1055/a-1076-3866 · W3043710859
Review OA: closed CC0
Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by qwen3.7-flash, 2026-09-08 ⓘ

This paper examines the clinical utility of combined oral contraceptives for endometriosis prophylaxis and therapy, noting that despite positive clinical experiences, recent doubts exist regarding their effectiveness for dysmenorrhea associated with the condition.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-08 · read from full text ⓘ

This editorial article examines the clinical utility of combined oral contraceptives for the prevention and treatment of endometriosis, noting recent doubts regarding their efficacy in managing dysmenorrhea associated with the condition. The authors review existing literature, including meta-analyses and randomized trials, to evaluate whether these hormonal agents effectively suppress lesion recurrence or alleviate pain symptoms in affected patients. Key considerations include the potential impact on ovarian reserve and the comparative effectiveness of progestin-only options versus estrogen-containing formulations in different patient populations. This paper is centrally about endometriosis — specifically evaluating the role of oral contraceptives in its prophylaxis and therapy.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Trotz guter Erfahrungen in der klinischen Praxis gibt es aktuell auch Zweifel am Nutzen der Anwendung von kombinierten östrogenhaltigen Kontrazeptiva (KOK) bei Dysmenorrhö, wenn diese ein Symptom der Endometriose ist 1.
Full text 3,333 characters · extracted from oa-doi-fallback · click to expand
Subscribe to RSS Please copy the URL and add it into your RSS Feed Reader. https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000020.xml Geburtshilfe Frauenheilkd 2020; 80(07): 672-674 DOI: 10.1055/a-1076-3866 DOI: 10.1055/a-1076-3866 GebFra Magazin Aktuell diskutiert Haben orale Kontrazeptiva einen Stellenwert für die Prophylaxe und Therapie der Endometriose? Authors Trotz guter Erfahrungen in der klinischen Praxis gibt es aktuell auch Zweifel am Nutzen der Anwendung von kombinierten östrogenhaltigen Kontrazeptiva (KOK) bei Dysmenorrhö, wenn diese ein Symptom der Endometriose ist [1]. Publication History Article published online: 14 July 2020 Georg Thieme Verlag KG Stuttgart · New York - Literatur - 1 Chapron C, Souza C, Borghese B. et al. Oral contraceptives and endometriosis: phe past use of oral contraceptives for treating severe primary dysmenorrhea is associated with endometriosis, especially deep infiltrating endometriosis. Hum Reprod 2011; 26: 2028-2035 - 2 Koga K, Takamura M, Fujii T. et al. Prevention of the recurrence of symptom and lesions after conservative surgery for endometriosis. Fertil Steril 2015; 104: 793-801 - 3 Vercellini P, Eskenazi B, Consonni D. et al. Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis. Hum Reprod Update 2011; 17: 159-170 - 4 Barbieri RL. Hormone treatment of endometriosis. The estrogen threshold hypothesis. Am J Obstet Gynecol 1992; 166: 740-745 - 5 Deb S, Campbell BK, Pincott-Allen C. et al. Quantifying effect of combined oral contraceptive pill on functional ovarian reserve as measured by serum anti-Müllerian hormone and small antral follicle count using three-dimensional ultrasound. Ultrasound Obstet Gynecol 2012; 39: 574-580 - 6 Dunselman GA, Vermeulen N, Becker C. et al. European Society of Human Reproduction and Embryology. ESHRE guideline: management of women with endometriosis. Hum Reprod 2014; 29: 400-412 - 7 Brown J, Crawford TJ, Datta S. et al. Oral contraceptives for pain associated with endometriosis. Cochrane Database Syst Rev 2018; (05) CD001019 - 8 Casper RF. Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills. Fertil Steril 2017; 107: 533-536 - 9 Jenkins TR, Liu CY, White J. Does response to hormonal therapy predict presence or absence of endometriosis?. J Minim Invasive Gynecol 2008; 15: 82-86 - 10 Harada T, Momoeda M, Taketani Y. et al. Low-dose oral contraceptive pill for dysmenorrhea associated with endometriosis. A placebo-controlled, double-blind, randomized trial. Fertil Steril 2008; 90: 1583-1588 - 11 Tandoi I, Somigliana E, Riparini J. et al. High rate of endometriosis recurrence in young women. J Pediatr Adolesc Gynecol 2011; 24: 376-379 - 12 Vercellini P, Somigliana E, Daguati R. et al. Postoperative oral contraceptive exposure and risk of endometrioma recurrence. Am J Obstet Gynecol 2008; 198: 504.e1-504.e5 - 13 Nezhat F, Nezhat C, Allan CJ. et al. Clinical and histologic classification of endometriomas. Implications for a mechanism of pathogenesis. J Reprod Med 1992; 37: 771-776 - 14 Herbel J. Untersuchungen zur Expression und endokrinen Regulation der epidermal growth factor receptor Familie in endometriotischen Läsionen [Dissertation]. Berlin: Charité – Universitätsmedizin Berlin; 2007

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

die_deep_infiltrating

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-10-26T06:31:53.434635+00:00
License: CC0 · commercial use OK