[Danazol in the treatment of endometriosis]

Terapevticheskii arkhiv · 1994 · vol. 66(10) , pp. 55–7 · PMID:7863449 · W2993877089
Non-randomised trial OA: closed CC0
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Danazol treatment (200-400 mg/day for 6 months) in 63 endometriosis patients resulted in 37 cures, 14 improvements, and 3 pregnancies, with rare side effects.

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Abstract

48 females with uterine endometriosis stage 1 and 2, 26 female with mild and moderate external endometriosis and 9 females with external in combination with internal endometriosis with the disease duration from 6 months to 10 years were given danazol in doses 200-400 mg/day for 6 months. The effect of the treatment proved to be very high: 37 patients were cured, 14 improved, 3 got pregnant. 11 patients needed the second treatment course. Side effects were rare. Depressed hyperactive menstrual cycle normalized quickly. It is inferred that danazol doses 200-400 mg/day are adequate for induction of complete or partial responses in internal and external endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Danazol Endometriosis Uterine Diseases Adult Adult Chronic Disease Chronic Disease Danazol Danazol Danazol Drug Evaluation Drug Evaluation Endometriosis Endometriosis Endometriosis Female Female Humans Humans Hysteroscopy

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License: CC0 · commercial use OK