Low prevalence of germline BRCA1 mutations in early onset breast cancer without a family history

D Ellis, Ellis D, Greenman J, J Greenman, S Hodgson, Hodgson S, S McCall, McCall S, Lalloo F, F Lalloo, Cameron J, J Cameron, L Izatt, Izatt L, Scott G, G Scott, C Jacobs, Jacobs C, Watts S, S Watts, Chorley W, W Chorley, C Perrett, Perrett C, Macdermot K, K Macdermot, Mohammed S, S Mohammed, Evans DG, G Evans, Mathew CG, C G Mathew
Journal of medical genetics · 2000 · vol. 37(10) , pp. 792–4 · doi:10.1136/jmg.37.10.792 · PMID:11183185 · PMC1757159
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This study investigated germline BRCA1 mutations in early-onset breast cancer patients who lacked a family history of the disease.

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MeSH descriptors

Breast Neoplasms Breast Neoplasms Gene Frequency Germ-Line Mutation Adult Age of Onset Base Sequence Breast Neoplasms Codon, Terminator Codon, Terminator Databases as Topic DNA Mutational Analysis Exons Exons Female Gene Frequency Genetic Testing Genetic Variation Genetic Variation Germ-Line Mutation

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