The Pathogenesis of Adenomyosis

Adenomyosis refers to an estrogen-dependent gynecological benign disease in which the endometrial glands and stroma invade the myometrium, resulting in localized or diffuse adenomyosis. It often combines with uterine fibroids, endometrial polyps, endometriosis, etc. The incidence of adenomyosis ranges from 1 to 70% [1] due to the variation of diagnostic criteria. The main clinical manifestations are progressive dysmenorrhea, chronic pelvic pain, menorrhagia, and infertility. With the improvement of magnetic resonance imaging (MRI), transvaginal ultrasound imaging, and other examination techniques, the detection rate of adenomyosis is also increasing [2, 3]. Although it has been nearly 100 years since the name of the disease is mentioned, the true pathogenesis of adenomyosis is still a mystery. This chapter will discuss and focus on the latest knowledge in the pathogenesis of adenomyosis. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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