Морфологическая, иммуногистохимическая и ультраструктурная характеристика синдрома хронической тазовой боли при наружном генитальном эндометриозе

The results of studying 60 cases external genital endometriosis have shown that one of mechanisms of pain occurrence is caused by inflammation at which there is a direct irritation of nerve ending by inflammation mediators leading to ultrastructural changes in nervous fibres and development of pain syndrome. Direct correlation dependence between expressiveness of vanilloid type 1 receptors in ectopic endometrium and the intensity of pain syndrome that opens prospects for pharmacological block TRPV1 is revealed and can be pathogenetic treatment of pain syndrome at endometriosis.