Uterine enzyme changes in thyroidectomized rats at parturition

Lab / animal OA: bronze CC0
⚙ AI-generated summary by qwen3.7-flash, 2026-10-10 ⓘ

Thyroidectomy in pregnant rats significantly altered uterine acid phosphatase, alkaline phosphatase, and transaminase activities at parturition depending on the timing of gland removal.

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Abstract

Rats were thyroidectomized at different stages of gestation and killed at parturition. Acid phosphatase of uterine horns was significantly (P < 0.05) lower in animals thyroidectomized at later stages of pregnancy, whereas alkaline phosphatase was significantly lower in those thyroidectomized earlier as compared to intact pregnant animals. The activities of glutamic oxaloacetic acid and glutamic pyruvic acid transaminases also showed significant alterations in some of the thyroidectomized animals. These 4 enzymes were also studied in the cervix but the changes showed a less distinct pattern.

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MeSH descriptors

Labor, Obstetric Uterus Acid Phosphatase Acid Phosphatase Alanine Transaminase Alanine Transaminase Alkaline Phosphatase Alkaline Phosphatase Animals Aspartate Aminotransferases Aspartate Aminotransferases Cervix Uteri Cervix Uteri Female Pregnancy Rats Thyroidectomy Uterus

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:58:49.153990+00:00
License: CC0 · commercial use OK