[Serum levels of proinflammatory cytokines in women with uterine myomas]
Observational
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CC0
⤵ 4 in-corpus citations
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This study measured serum levels of IL-1 alpha, IL-6, and TNF-alpha in women with uterine myomas, finding significantly elevated IL-1 alpha in patients compared to controls.
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Abstract
The levels of proinflammatory cytokines, namely IL-1 alpha, IL-6 and TNF-alpha were determined in blood serum of 26 women with uterine myomas and in 20 healthy controls. A significantly elevated concentration of IL-1 alpha was found in patients with uterine myomas. Levels of IL-6 and TNF-alpha were insignificantly higher in women with myomas. The obtained results indicate the possible role of IL-1 alpha in the pathogenesis of uterine myomas--further studies are needed to elucidate the role of proinflammatory cytokines in the proliferative disorders of myometrium.
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Cited by (4)
- Evaluation of monocyte chemotactic protein-1 levels in peripheral blood of infertile women with endometriosis 2005
- Are uterine leiomyoma a consequence of a chronically inflammatory immune system? 2012
- Cyclooxygenase-2 inhibitor, celecoxib, inhibits leiomyoma cell proliferation through the nuclear factor κB pathway 2014
- CYTOKINE EXPRESSION PROFILES OF PERITONEAL FLUID IN THE PATIENTS WITH UTERINE LEIOMYOMA 2014
Cited by (4)
- CYTOKINE EXPRESSION PROFILES OF PERITONEAL FLUID IN THE PATIENTS WITH UTERINE LEIOMYOMA 2014
- Cyclooxygenase-2 inhibitor, celecoxib, inhibits leiomyoma cell proliferation through the nuclear factor κB pathway 2014
- Are uterine leiomyoma a consequence of a chronically inflammatory immune system? 2012
- Evaluation of monocyte chemotactic protein-1 levels in peripheral blood of infertile women with endometriosis 2005
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:00:24.492322+00:00
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